Toward Cancer Biomarker Discovery using the Glycomics Approach
نویسندگان
چکیده
منابع مشابه
Toward cancer biomarker discovery using the glycomics approach.
Following on from genomics and proteomics, glycomics has become one of the most important research fields in recent years. The techniques for glycomics are rather complicated as compared to those for genomics and proteomics because glycans are very heterogeneous and there are no amplifying or cloning techniques such as those for PCR or molecular cloning, nor are there any synthesizers or sequen...
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Glycosylation is highly sensitive to the biochemical environment and plays a key role in development and disease manifestation. Moreover, glycan biosynthesis depends on several highly competitive processes; thus, variations in the concentration of specific glycosyltransferases produce different products. For this reason, monitoring changes in glycosylation may be a more specific and sensitive a...
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ژورنال
عنوان ژورنال: PROTEOMICS
سال: 2008
ISSN: 1615-9853,1615-9861
DOI: 10.1002/pmic.200890056